| Baclofen | 10 mg x 60 pills | 10 mg x 90 pills |
| $ 00.85 | $ 57.60 | $ 76.50 |
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| 25 mg x 30 pills | 25 mg x 60 pills | 25 mg x 90 pills |
| $ 93.90 | $ 171.00 | $ 251.10 |
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baclofen
Baclofen 20 mg
Chemical composition:
Acid beta-[aminomethyl]-p-hydroxycinnamic.
The structure of baclofen is similar to derivative gamma-amino butyric acid (Gamma-amino butyric acid is a biogenic substance. It is contained in the central nervous system and it take part in metabolic processes in the brain) aminalon and phenibut. It differs from the last because it contains atom of chlorine in the para-position of the phenol nucleus.
Synonyms: Baclon, Gabalon, Lioresal, Spastin.
Category: Medicines that act primarily on the central nervous system. Different drugs to control convulsions.
The form release baclofen 20 mg:
Available in tablets of 10 and 25 mg.
Pill white, round, biconvex, with a mark of division by half.
The only difference between 20 mg to 10 mg is the greater concentration of an active material that makes it easier to calculate the optimal therapeutic dose.
Packing:
In vial there are 25 mg x 30 pills, 25 mg x 60 pills, 25 mg x 90 pills. In a carton box there is 1 vial.
The main composition includes no active ingredients: lactose, potato starch, gelatin, talc, magnesium.
The recommended doses. Side effects and limitations. Warning: see baclofen 10 mg.
General description: buy baclofen online
Pharmacological properties:
In the first place there is rather strong antidepressant effect. The medicine, which reduces the tone of skeletal muscles. It has a good effect on a relaxation of the skeletal (striated) muscle tissue by means of the alpha motor system, reducing anxiety, as well as by reducing the activity of gamma sensitive. Baclofen has a braking effect on mono-and polysynaptic reflex. While it neither reduce the nerve conduction of muscles within the doyere's eminence, nor sensitivity of sensory endings of muscle spindles. It is a strong analgesic, thereby it increases motor and functional activity of patients, facilitating the restorative treatment. Baclofen is the most useful in the treatment of spastic states in case of multiple sclerosis. The drug can also be used for some spastic states of cerebral origin.
Interaction with other substances:
simultaneous usage of baclofen 20 mg with the other drugs, affecting the central nervous system, amplifies the sedation.
- Lithium salts – amplification of the hyperkinetic symptoms.
- Antidepressants – increase the action with a significant decrease in muscle tone.
- With medicines which have the property of reducing high blood pressure - increased blood pressure in consequence of which may require dosage adjustment.
- Medicines whose usage can lead to renal failure (for example Ibuprofen) - excretion of the drug becomes slower and may increase its toxic effects.
- Carbidopa and levodopa - in patients with Parkinson's disease may demonstration of confusion, hallucinations and hyperexcitability.
- Fentanyl - prolongs analgesic action.
- The usage of baclofen 20 mg with the alcohol - very strongly amplifies the action of alcoholic beverages.
Overdose:
Acute poisoning of baclofen 20 mg may be accompanied by insomnia, loss of consciousness, coma, respiratory failure. May also develop dizziness, hallucinations, anxiety, disturbance of accommodation, loss of eye reaction to the light, muscular hypotonia, hyporeflexia, convulsions, peripheral relaxation of smooth muscle in blood vessel walls, bradycardia, decrease in body temperature, nausea, vomiting, and diarrhea. Visual signs of light toxicity may include: elevated mood, spontaneous laughter, sleeping is characterized by loss of the sense of time, may be delusions and hallucinations, amplification of brightness of colors, a strong antidepressant effect, a strong increase in sexual desire, medium dryness in mouth, loss of self-control is also observed.
Treatment of overdose:
It is necessary to rinse the stomach and appoint the absorbent carbon. If necessary, use laxatives. For patients in a comatose state, before the rinse the stomach is necessary put in a special tube into the larynx and trachea in their restriction to avoid suffocation. Carry out maintenance the functions of respiratory and cardiovascular systems. No specific antidote.
In case of the mild forms of intoxication to eliminate unwanted effects on the central nervous system, especially in insomnia and respiratory depression, intravenous physostigmine (1-2 mg for 5-10 minutes). If after the first dose the patient's condition has not improved enter again after 30-60 minutes. To increase elimination of baclofen 20 mg from the organism the method of forced withdrawal of urine is used. In convulsions it is necessary intravenous valium.
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May. 23, 2011